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10.1016/j.molcel.2018.08.004 Mol Cell

In EGFR-mutant NSCLC, multiple approaches have been shown to restore sensitivity by activating ferroptosis

Preliminary animal studies show that exercise in high-fat diet mice resulted in reduced hepatic 4-HNE levels and upregulation of anti-apoptotic protein expression (Merry and Ristow, 2016)